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Browsing by Author "Aramburu, José (Aramburu Beltrán)"

Browsing by Author "Aramburu, José (Aramburu Beltrán)"

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  • The role of CDKN1B-p27kip1 deregulation in the pathogenesis of pediatric T-cell acute lymphoblastic leukemia
    Colomer-Lahiguera, Sara (Universitat Pompeu Fabra, 2018-05-02)
    T-cell acute lymphoblastic leukemia (T-ALL) accounts for 10 15% of pediatric ALL. The oncogenic transformation of T-cell precursors is driven by a broad spectrum of genetic abnormalities. We have confirmed the high frequency ...
  • The transcription factor NFAT5 limits infection-induced type I interferon responses
    Huerga Encabo, Hector, 1989-; Traveset Martínez, Laia, 1992-; Argilaguet Marqués, Jordi, 1977-; Angulo Aguado, Ana; Nistal-Villán, Estanislao; Jaiswal, Rahul; Escalante, Carlos R.; Gekas, Christos; Meyerhans, Andreas; Aramburu, José (Aramburu Beltrán); López Rodríguez, M. Cristina (Rockefeller University Press, 2020)
    Type I interferon (IFN-I) provides effective antiviral immunity but can exacerbate harmful inflammatory reactions and cause hematopoietic stem cell (HSC) exhaustion; therefore, IFN-I expression must be tightly controlled. ...
  • Transcription factors and target genes of pre-TCR signaling
    López Rodríguez, M. Cristina; Aramburu, José (Aramburu Beltrán); Berga-Bolaños, Rosa (Springer, 2015)
    Almost 30 years ago pioneering work by the laboratories of Harald von Boehmer and Susumo Tonegawa provided the first indications that developing thymocytes could assemble a functional TCRβ chain-containing receptor complex, ...
  • Transcriptional regulation of gene expression during osmotic stress responses by the mammalian target of rapamycin
    Ortells Campos, Mª Carmen, 1984-; Morancho Armisen, Beatriz; Drews-Elger, Katherine, 1978-; Viollet, Benoit; Laderoute, Keith R; López Rodríguez, M. Cristina; Aramburu, José (Aramburu Beltrán) (Oxford University Press, 2012)
    Although stress can suppress growth and proliferation, cells can induce adaptive responses that allow them to maintain these functions under stress. While numerous studies have focused on the inhibitory effects of stress ...

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