Browsing by Author "Albà Soler, Mar"

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  • Blanco, Enrique; Farré, Domènec; Albà Soler, Mar; Messeguer, Xavier; Guigó Serra, Roderic (Oxford University Press, 2006)
    Information about the genomic coordinates and the sequence of experimentally identified transcription factor binding sites is found scattered under a variety of diverse formats. The availability of standard collections of ...
  • Shikhagaie, Medya (Universitat Pompeu Fabra, 2012-01-26)
    In the present study, we have approached the molecular characterization of the HCMV specific UL1. To this end a HCMV (AD169-derived HB5 background) recombinant with an HA-epitope tagged UL1 and a mutant with a full UL1 ...
  • Mulero, María Carmen; Islam, Abul, 1978-; Margalef González, Pol, 1985-; Pecoraro, Matteo, 1984-; Toll Abelló, Agustín; Drechsel, Nils Jan Daniel, 1980-; Charneco, Cristina; Bellora Pereyra, Nicolás; Gallardo Hernández, Fernando; López Arribillaga, Erika, 1986-; Asensio Juan, Elena; Rodilla, Verónica; González, Jessica; Iglesias Coma, Mar; Albà Soler, Mar; Di Croce, Luciano; Villà i Freixa, Jordi; López Bigas, Núria; Keyes, William M., 1973-; Bigas Salvans, Anna; Espinosa Blay, Lluís (Elsevier, 2013)
    IκB proteins are the primary inhibitors of NF-κB. Here, we demonstrate that sumoylated and phosphorylated IκBα accumulates in the nucleus of keratinocytes and interacts with histones H2A and H4 at the regulatory region of ...
  • Albà Soler, Mar; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2004)
    Amino acid tandem repeats, also called homopolymeric tracts, are extremely abundant in eukaryotic proteins. To gain insight into the genome-wide evolution of these regions in mammals, we analyzed the repeat content in a ...
  • Mularoni, Loris (Universitat Pompeu Fabra, 2011-04-12)
    Tandem amino acid repeats, also known as homopolimeric tract or homopeptides, are very common features of eukaryotic genomes and are present in nearly one-fifth of human encoded proteins. These structures have attracted ...
  • Gröger, Anna; Martínez-Albo, Ilune; Albà Soler, Mar; Ayté del Olmo, José; Vega, Montserrat; Hidalgo Hernando, Elena (MDPI, 2023)
    Aging is characterized by a number of hallmarks including loss of mitochondrial homeostasis and decay in stress tolerance, among others. Unicellular eukaryotes have been widely used to study chronological aging. As a general ...
  • Ruiz-Orera, Jorge; Albà Soler, Mar (Oxford University Press, 2020)
    The mammalian transcriptome includes thousands of transcripts that do not correspond to annotated protein-coding genes and that are known as long non-coding RNAs (lncRNAs). A handful of lncRNAs have well-characterized ...
  • Hernández-Fernández, Javier; Pinzón Velasco, Andrés Mauricio; López Barrera Ellie Anne; Rodríguez Becerra, María Del Pilar; Villanueva Cañas, José Luis, 1984-; Albà Soler, Mar; Mariño Ramírez, Leonardo (Corte Madera, CA : PeerJ Inc., 2021)
    The aim of this study was to generate and analyze the atlas of the loggerhead turtle blood transcriptome by RNA-seq, as well as identify and characterize thioredoxin (Tnxs) and peroxiredoxin (Prdxs) antioxidant enzymes of ...
  • Furney, Simon J.; Albà Soler, Mar; López Bigas, Núria (BioMed Central, 2006)
    Background: Global analyses of human disease genes by computational methods have yielded important advances in the understanding of human diseases. Generally these studies have treated the group of disease genes uniformly, ...
  • Radó i Trilla, Núria, 1985-; Albà Soler, Mar (BioMed Central, 2012)
    Low-complexity regions (LCRs) in proteins are tracts that are highly enriched in one or a few aminoacids. Given their high abundance, and their capacity to expand in relatively short periods of time through replication ...
  • Ledda, Alice (Universitat Pompeu Fabra, 2011-06-21)
    Els microsat el lits s on seq u encies d'ADN formades per repeticions en t andem de motius curts. Les curtes seq u encies repetides en t andem s on ubiq ues en els genomes dels eucariotes, tant en les regions codi cants ...
  • Toll i Riera, Macarena, 1984-; Albà Soler, Mar (BioMed Central, 2013)
    Proteins are composed of a combination of discrete, well-defined, sequence domains, associated with specific functions that have arisen at different times during evolutionary history. The emergence of novel domains is ...
  • Huang, Hui; Winter, Eitan E; Wang, Huajun; Weinstock, Keith G; Xing, Heming; Goodstadt, Leo; Stenson, Peter D; Cooper, David N; Smith, Douglas; Albà Soler, Mar; Ponting, Chris P; Fechtel, Kim (BioMed Central, 2004)
    Background: Model organisms have contributed substantially to our understanding of the etiology of human disease as well as having assisted with the development of new treatment modalities. The availability of the human, ...
  • Blevins, William Robert (Universitat Pompeu Fabra, 2020-01-22)
    All living organisms respond to environmental stimuli by modulating the activity of different genes. This response can occur across many locations throughout the cell such as at the level of transcription, translation, and ...
  • Montañés, José Carlos; Huertas, Marta; Messeguer, Xavier; Albà Soler, Mar (Oxford University Press, 2023)
    The formation of new genes during evolution is an important motor of functional innovation, but the rate at which new genes originate and the likelihood that they persist over longer evolutionary periods are still poorly ...
  • Blevins, William Robert, 1987-; Tavella, Teresa; Moro, Simone G.; Blasco Moreno, Bernat, 1986-; Closa-Mosquera, Adrià; Díez Antón, Juana, 1962-; Carey, Lucas, 1980-; Albà Soler, Mar (Nature Research, 2019)
    Cells responds to diverse stimuli by changing the levels of specific effector proteins. These changes are usually examined using high throughput RNA sequencing data (RNA-Seq); transcriptional regulation is generally assumed ...
  • Faherty, Sheena L.; Villanueva Cañas, José Luis, 1984-; Klopfer, Peter H.; Albà Soler, Mar; Yoder, Anne D. (Oxford University Press, 2016)
    Hibernation is a complex physiological response that some mammalian species employ to evade energetic demands. Previous work in mammalian hibernators suggests that hibernation is activated not by a set of genes unique to ...
  • Santpere Baró, Gabriel, 1981-; Darre, Fleur; Blanco, Soledad; Alcami, Antonio; Villoslada, Pablo; Albà Soler, Mar; Navarro i Cuartiellas, Arcadi, 1969- (Oxford University Press, 2014)
    Most people in the world (∼90%) are infected by the Epstein–Barr virus (EBV), which establishes itself permanently in B cells. Infection by EBV is related to a number of diseases including infectious mononucleosis, multiple ...
  • Baldo, Laura; Riera, Joan Lluís; Tooming-Klunderud, Ave; Albà Soler, Mar; Salzburger, Walter (Public Library of Science, 2015)
    The gut microbiota structure reflects both a host phylogenetic history and a signature of adaptation to the host ecological, mainly trophic niches. African cichlid fishes, with their array of closely related species that ...
  • Hong, Shin-Young; Sun, Bin; Straub, Daniel; Blaakmeer, Anko; Mineri, Lorenzo; Koch, Jonas; Brinch-Pedersen, Henrik; Holme, Inger B.; Burow, Meike; Lyngs Jørgensen, Hans Jørgen; Albà Soler, Mar; Wenkel, Stephan (National Academy of Sciences, 2020)
    MicroProteins are small, often single-domain proteins that are sequence-related to larger, often multidomain proteins. Here, we used a combination of comparative genomics and heterologous synthetic misexpression to isolate ...

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