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We study optimal monetary policy during times of global scarcity of tradable goods. The optimal monetary response entails a surge in inflation, which helps rebalance production toward the tradable sector. While the inflation costs are fully borne domestically, however, the gains in terms of higher supply of tradable goods partly spill over to the rest of the world. National central banks may thus fall into a coordination trap and implement an excessively tight monetary policy causing an unnecessarily sharp global contraction.
(2026) Fornaro, Luca; Romei, Federica
In this chapter we analyse the case of young women as social actors based on a study carried out by the Research Group on Youth, Society and Communication (https://www.upf.edu/web/joviscom/inici). We focus on the perspectives of young women and their awareness and discourses on feminism, as well as on the empowerment they gain from participating in organized groups or associations that are not defined as explicitly feminist. Based on qualitative and ethnographic research carried out between 2017 and 2019, we focus on the different ways in which young women in different cities in Catalonia (Spain) think about and experience gender and equality relations. In this chapter, we will present the results of life histories to explain how different intersectional variables are interrelated with autobiographical and family components and we will also carefully analyse the role of social networks. The research shows very different images of the participants according to the study method used. While in their Instagram profiles young women contribute to the objectification of their bodies and reproduce the established canons, the interviews showed that they had critical discourses about the representation of women in social media.
(2021) Figueras Maz, Mònica; Arciniega Cáceres, Mittzy; Hansen, Nele; Strecker, Tanja
Heart transplantation (HT) is the gold standard therapy for advanced heart failure (ADHF), and LVADs as destination therapy are an option in non-HT candidates. Most patients with ADHF never receive HT or an LVAD, so alternative strategies are needed. Intermittent levosimendan can reduce HF hospitalizations in ADHF patients in the short term. It is uncertain whether the results of the comparison of inotropes with older-generation LVADs would have the same outcomes in the current era of ADHF patients treated with levosimendan, who are less sick but older. In this paper, we compare the use of two therapeutic strategies for end-stage HF in patients who are not candidates for HT: repetitive intermittent levosimendan vs. LVAD as destination therapy. To do so, we compare two multicenter cohorts of real-life patients from Spain: the LEVO-D registry and the REGALAD registry. In total, 715 patients coming from the two registries were found: 403 from LEVO-D and 312 from REGALAD. Non-adjusted median survival was shorter for LEVO-D patients, with the benefit for the LVADs seen only after the first year of therapy. The survival advantage for the LVAD cohort was also true after analysis of the matched cohort but, as in the non-matched analysis, the survival benefit was mainly shown after one year of follow-up. We conclude that in elderly ADHF non-HT candidates, LVAD therapy offers significantly better long-term outcomes when compared to intermittent levosimendan; thus, it should be considered in carefully selected candidates. On the other hand, in poor LVAD candidates or highly comorbid patients, intermittent inotropic support with levosimendan could be a reasonable alternative to LVAD, as 1-year outcomes are similar.
(2024) Dobarro, David; Ruiz-Bustillo, Sonia; González-Costello, José
Josep Puig i Cadafalch és principalment conegut, a Europa i els Estats Units, com a historiador de l'art romànic. Si bé la seva relació intel·lectual amb França és àmpliament coneguda, fins ara no s'ha parat prou atenció als seus contactes amb altres països. Basant- se principalment en els materials fins ara inèdits del Fons Puig i Cadafalch de l'Arxiu Nacional de Catalunya, aquest article explora les relacions de Puig més enllà del nucli francès, tot parant una atenció especial al cas de Romania. S'analitza el paper que l'estudi de les esglésies policromades de Moldàvia va tenir en la seva teoria sobre l'origen i evolució del primer art romànic, així com la dimensió política dels seus contactes amb Nicolae Iorga i altres intel·lectuals romanesos de primer ordre. A partir d'aquests nous materials, l'article pretén replantejar la naturalesa de la filiació de Puig al positivisme historiogràfic, així com oferir una nova perspectiva sobre la continuïtat de la seva activitat política i de recerca abans i després del cop d'estat de Primo de Rivera el 1923.
(2021) Mallart, Lucila
BACKGROUND: Abdominal aortic aneurysms (AAAs) are focal dilatations of the abdominal aorta that expand progressively, increasing their risk of rupture. Rupture of an AAA is associated with high mortality rates, but the mechanisms underlying the initiation, expansion, and rupture of AAAs are not yet fully understood. We aimed to characterize the pathophysiology of AAAs and identify new genes associated with AAA initiation and progression. METHODS AND RESULTS: This study used RNA sequencing data on 140 samples, becoming the largest RNA sequencing data set for differential expression studies of AAAs. We performed differential expression analyses and analyses of differential splicing between dilated and nondilated aortic tissue samples, and between AAAs of different diameters. We identified 3002 differentially expressed genes between AAAs and controls that were independent of ischemic time, 1425 of which were new. Additionally, 8 genes (EXTL3, ZFR, DUSP8, DISP1, USP33, VPS37C, ZNF784, RFX1) were differentially expressed between AAAs of varying diameters and between AAAs and control samples. Finally, 7 genes (SPP1, FHL1, GNAS, MORF4L2, HMGN1, ARL1, RNASE4) with differential splicing patterns were also differentially expressed genes between AAAs and controls, sug-gesting that splicing differences in these genes may contribute to the observed expression changes and disease development. CONCLUSIONS: This study identifies new genes and splicing patterns associated with AAAs and validates previous relevant pathways on AAAs. These findings contribute to the understanding of the complex mechanisms underlying AAAs and may provide potential targets to limit AAA progression and mortality risk.
(2024) Temprano-Sagrera, Gerard; Peypoch, Olga; Soto, Begoña; Dilmé, Jaume; Calsina Juscafresa, Laura; Davtian, David; Estadella, Mireia de la Rosa; Nieto, Lluis; Brown, Andrew; Escudero, José Román; Viñuela, Ana; Camacho, Mercedes; Sabater-Lleal, Maria