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El repositorio institucional recoge, difunde y preserva la producción intelectual en formato digital que resulta de la actividad académica e investigadora de la UPF, las revistas científicas y las publicaciones institucionales. Su finalidad es contribuir a aumentar el impacto de la investigación hecha en la UPF y preservar la memoria intelectual de la UPF.

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Influencia de la victimización infantil en la percepción de los agresores domésticos y sexuales

Quintana de Portafax, Nuria (2023-06-23)
Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson’s disease

Alvarez Jerez, Pilar; Alcantud, Jose Luis; Reyes-Ramírez, Lucia de los; Moore, Anni; Ruz, Clara; Vives Montero, Francisco; Rodriguez-Losada, Noela; Saini, Prabhjyot; Gan-Or, Ziv; Alvarado, Chelsea X.; Makarious, Mary B.; Billingsley, Kimberley J.; Blauwendraat, Cornelis; Noyce, Alastair J.; Singleton, Andrew B.; Duran, Raquel; Bandres-Ciga, Sara (Nature Research, 2023)

Neurodegeneration with brain iron accumulation (NBIA) represents a group of neurodegenerative disorders characterized by abnormal iron accumulation in the brain. In Parkinson's Disease (PD), iron accumulation is a cardinal ...
Automated optimisation of solubility and conformational stability of antibodies and proteins

Rosace, Angelo; Bennett, Anja; Oeller, Marc; Mortensen, Mie M.; Sakhnini, Laila; Lorenzen, Nikolai; Poulsen, Christian; Sormanni, Pietro (Nature Research, 2023)

Biologics, such as antibodies and enzymes, are crucial in research, biotechnology, diagnostics, and therapeutics. Often, biologics with suitable functionality are discovered, but their development is impeded by developability ...
Robustness and innovation in synthetic genotype networks

Santos-Moreno, Javier; Tasiudi, Eve; Kusumawardhani, Hadiastri; Stelling, Joerg; Schaerli, Yolanda (Nature Research, 2023)

Genotype networks are sets of genotypes connected by small mutational changes that share the same phenotype. They facilitate evolutionary innovation by enabling the exploration of different neighborhoods in genotype space. ...
Natural green spaces, sensitization to allergens, and the role of gut microbiota during infancy

Buchholz, Vienna; Bridgman, Sarah L.; Nielsen, Charlene C.; Gascon Merlos, Mireia, 1984-; Tun, Hein M.; Simons, Elinor; Turvey, Stuart E.; Subbarao, Padmaja; Takaro, Tim K.; Brook, Jeffrey R.; Scott, James A.; Mandhane, Piush J.; Kozyrskyj, Anita L. (American Society for Microbiology, 2023)

The environment plays an instrumental role in the developmental origins of health and disease. Protective features of the environment in the development of asthma and atopy have been insufficiently studied. We used data ...