• A new assemblage of late Neanderthal remains from Cova Simanya (NE Iberia)

  Morales, Juan I.; Cebrià, Artur; Soto, María; Rodríguez-Hidalgo, Antonio; Hernando, Raquel (Frontiers, 2023)
• Increased paclitaxel recovery from Taxus baccata vascular stem cells using novel in situ product recovery approaches

  Santoyo-Garcia, Jorge H.; Valdivia-Cabrera, Marissa; Ochoa-Villarreal, Marisol; Casasola-Zamora, Samuel; Ripoll, Magdalena; Escrich Montañana, Ainoa; Moyano Claramunt, Elisabet; Betancor, Lorena; Halliday, Karen J.; Loake, Gary J.; Rios-Solis, Leonardo (Springer, 2023)

  In this study, several approaches were tested to optimise the production and recovery of the widely used anticancer drug Taxol® (paclitaxel) from culturable vascular stem cells (VSCs) of Taxus baccata, which is currently ...
• Classification system for nanotechnology-enabled health products with both scientific and regulatory application

  Rivera Gil, Pilar (Frontiers, 2023)
• Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

  Maury, Eduardo A.; Brain Somatic Mosaicism Network; Walsh, Christopher A. (Elsevier, 2023)

  While germline copy-number variants (CNVs) contribute to schizophrenia (SCZ) risk, the contribution of somatic CNVs (sCNVs)-present in some but not all cells-remains unknown. We identified sCNVs using blood-derived genotype ...
• A quantitative systems pharmacology model for certolizumab pegol treatment in moderate-to-severe psoriasis

  Coto-Segura, Pablo; Segú-Vergés, Cristina; Martorell, Antonio; Moreno-Ramírez, David; Jorba Argemí, Guillem; Junet, Valentin; Guerri, Filippo; Daura, Xavier; Oliva Miguel, Baldomero; Cara, Carlos; Suárez-Magdalena, Olaya; Abraham, Sonya; Mas, José Manuel (Frontiers, 2023)

  Background: Psoriasis is a chronic immune-mediated inflammatory systemic disease with skin manifestations characterized by erythematous, scaly, itchy and/or painful plaques resulting from hyperproliferation of keratinocytes. ...

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