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Welcome to the UPF Digital Repository

The institutional repository collects, disseminates and preserves, in digital form, the intellectual output that results from the academic and research activity of the UPF and also the scientific magazines and the institutional publications. Its purpose is to increase the impact of research done at the UPF and its intellectual memory.

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Essays in macroeconomics

Hoesch, Lukas (Universitat Pompeu Fabra, 2021-11-08)

This thesis consists of three chapters on topics in Macroeconometrics. Chapter 1 develops a hypothesis test to evaluate economic models and their forecasts robust to instabilities. The test is particularly powerful in the ...
Influencia de la victimización infantil en la percepción de los agresores domésticos y sexuales

Quintana de Portafax, Nuria (2023-06-23)
Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson’s disease

Alvarez Jerez, Pilar; Alcantud, Jose Luis; Reyes-Ramírez, Lucia de los; Moore, Anni; Ruz, Clara; Vives Montero, Francisco; Rodriguez-Losada, Noela; Saini, Prabhjyot; Gan-Or, Ziv; Alvarado, Chelsea X.; Makarious, Mary B.; Billingsley, Kimberley J.; Blauwendraat, Cornelis; Noyce, Alastair J.; Singleton, Andrew B.; Duran, Raquel; Bandres-Ciga, Sara (Nature Research, 2023)

Neurodegeneration with brain iron accumulation (NBIA) represents a group of neurodegenerative disorders characterized by abnormal iron accumulation in the brain. In Parkinson's Disease (PD), iron accumulation is a cardinal ...
Automated optimisation of solubility and conformational stability of antibodies and proteins

Rosace, Angelo; Bennett, Anja; Oeller, Marc; Mortensen, Mie M.; Sakhnini, Laila; Lorenzen, Nikolai; Poulsen, Christian; Sormanni, Pietro (Nature Research, 2023)

Biologics, such as antibodies and enzymes, are crucial in research, biotechnology, diagnostics, and therapeutics. Often, biologics with suitable functionality are discovered, but their development is impeded by developability ...
Robustness and innovation in synthetic genotype networks

Santos-Moreno, Javier; Tasiudi, Eve; Kusumawardhani, Hadiastri; Stelling, Joerg; Schaerli, Yolanda (Nature Research, 2023)

Genotype networks are sets of genotypes connected by small mutational changes that share the same phenotype. They facilitate evolutionary innovation by enabling the exploration of different neighborhoods in genotype space. ...