Visualitza Articles (Departament de Medicina i Ciències de la Vida) per autoria "Yan, Minhong"

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Notch signal strength controls cell fate in the haemogenic endothelium.

Gama-Norton, Leonor; Ferrando Martorell, Eva, 1986-; Ruiz Herguido, Cristina; Liu, Zenhy; Guiu Sagarra, Jordi, 1983-; Islam, Abul, 1978-; Lee, Sung-Uk; Yan, Minhong; Guidos, Cynthia J.; López Bigas, Núria; Maeda, Takahiro; Espinosa Blay, Lluís; Kopan, Raphael; Bigas Salvans, Anna (Nature Publishing Group, 2015)

Acquisition of the arterial and haemogenic endothelium fates concurrently occur in the aorta-gonad-mesonephros (AGM) region prior to haematopoietic stem cell (HSC) generation. The arterial programme depends on Dll4 and the ...