Visualitza Articles (Departament de Medicina i Ciències de la Vida) per matèria "Ratolins -- Genètica"

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Enhanced transcriptome maps from multiple mouse tissues reveal evolutionary constraint in gene expression

Pervouchine, Dmitri D.; Djebali, Sarah; Breschi, Alessandra, 1988-; Prieto Barja, Pablo, 1986-; Lagarde, Julien; Bussotti, Giovanni, 1983-; Monlong, Jean; Notredame, Cedric; Guigó Serra, Roderic; Gingeras, Thomas R. (Nature Pub. Group, 2015)

Mice have been a long-standing model for human biology and disease. Here we characterize, by RNA sequencing, the transcriptional profiles of a large and heterogeneous collection of mouse tissues, augmenting the mouse ...
Improved definition of the mouse transcriptome via targeted RNA sequencing

Bussotti, Giovanni, 1983-; Leonardi, Tommaso; Clark, Michael B.; Mercer, Tim R.; Crawford, Joanna; Malquori, Lorenzo; Notredame, Cedric; Dinger, Marcel E.; Mattick, John S.; Enright, Anton J. (Cold Spring Harbor Laboratory Press (CSHL Press), 2016)

Targeted RNA sequencing (CaptureSeq) uses oligonucleotide probes to capture RNAs for sequencing, providing enriched read coverage, accurate measurement of gene expression, and quantitative expression data. We applied ...