Visualitza Articles (Departament de Medicina i Ciències de la Vida) per matèria "Neurolèptics"

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Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands

López Muñoz, Laura; Sanz, Ferran; Pastor Maeso, Manuel; Selent, Jana; Loza, María I.; Brea, José; Areias, Filipe; Ortega, Raquel; Masaguer, Christian F.; Raviña, Enrique (Elsevier, 2009)

A series of new benzolactam derivatives was synthesized and the derivatives were evaluated for their/naffinities at the dopamine D1, D2, and D3 receptors. Some of these compounds showed high D2 and/or/nD3 affinity and ...