Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Subject "Genètica"

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Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Subject "Genètica"

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  • Mann, Christopher J.; Perdiguero, Eusebio, 1968-; Kharraz, Yacine; Aguilar, Susana; Pessina, Patrizia; Serrano, Antonio L.; Muñoz Cánoves, Pura, 1962- (BioMed Central, 2011)
    The repair process of damaged tissue involves the coordinated activities of several cell types in response to local and systemic signals. Following acute tissue injury, infiltrating inflammatory cells and resident stem ...
  • Encode Project Consortium; Dunham I.; Guigó Serra, Roderic; Birney E. (Nature Publishing Group, 2012)
    The human genome encodes the blueprint of life, but the function of the vast majority of its nearly three billion bases is unknown. The Encyclopedia of DNA Elements (ENCODE) project has systematically mapped regions of ...
  • Jiménez Guri, Eva; Huerta Cepas, Jaime; Cozzuto, Luca; Wotton, Karl R.; Kang, Hui; Himmelbauer, Heinz; Roma, Guglielmo; Gabaldón Estevan, Juan Antonio, 1973-; Jaeger, Johannes (BioMed Central, 2013)
    BACKGROUND: Modern sequencing technologies have massively increased the amount of data available for comparative genomics. Whole-transcriptome shotgun sequencing (RNA-seq) provides a powerful basis for comparative studies. ...
  • Powell, Sean; Forslund, Kristoffer; Szklarczyk, Damian; Trachana, Kalliopi; Roth, Alexander; Huerta Cepas, Jaime; Gabaldón Estevan, Juan Antonio, 1973-; Rattei, Thomas; Creevey, Chris; Kuhn, Michael; Jensen, Lars J.; Mering, Christian von; Bork, Peer (Oxford University Press, 2014)
    With the increasing availability of various 'omics data, high-quality orthology assignment is crucial for evolutionary and functional genomics studies. We here present the fourth version of the eggNOG database (available ...
  • Djebali, Sarah; Lagarde, Julien; Lacroix, Vincent; Foissac, Sylvain; Ribeca, Paolo; Martin, David; Guigó Serra, Roderic; Gingeras, Thomas R. (Public Library of Science (PLoS), 2012)
    The classic organization of a gene structure has followed the Jacob and Monod bacterial gene model proposed more than 50 years ago. Since then, empirical determinations of the complexity of the transcriptomes found in yeast ...
  • González-Neira, Anna; Calafell i Majó, Francesc; Navarro Cuartiellas, Arcadi; Lao Grueso, Oscar, 1976-; Cann, Howard; Comas Martínez, David; Bertranpetit, Jaume, 1952- (BioMed Central, 2004)
    Recent studies of haplotype diversity in a number of genomic regions have suggested that long stretches of DNA are preserved in the same chromosome, with little evidence of recombination events. The knowledge of the extent ...
  • Djebali, Sarah; Merkel, Angelika; Tanzer, Andrea; Lagarde, Julien; Röder, Maik; Curado, Joao; Derrien, Thomas; Ferreira, Pedro; González, David; Johnson, Rory; Kingswood, Colin; Ribeca, Paolo; Sammeth, Michael; Skancke, Jorgen; Tilgner, Hagen; Guigó Serra, Roderic; Gingeras, Thomas R. (Nature Publishing Group, 2012)
    Eukaryotic cells make many types of primary and processed RNAs that are found either in specific subcellular compartments or throughout the cells. A complete catalogue of these RNAs is not yet available and their characteristic ...
  • Dong, Xianjun; Greven, Melissa C.; Kundaje, Anshul; Djebali, Sarah; Brown, James B.; Cheng, Chao; Gingeras, Thomas R.; Gerstein, Mark B.; Guigó Serra, Roderic; Birney, Ewan; Weng, Zhiping (BioMed Central, 2012)
    BACKGROUND: Previous work has demonstrated that chromatin feature levels correlate with gene expression. The ENCODE project enables us to further explore this relationship using an unprecedented volume of data. Expression ...
  • Khymenets, Olha; Fitó Colomer, Montserrat; Covas Planells, Maria Isabel; Farré Albaladejo, Magí; Pujadas, María Antonia; Muñoz Aguayo, Daniel; Konstantinidou, Valentini; De la Torre Fornell, Rafael (Mary Ann Liebert, Inc, 2009)
    Virgin olive oil (VOO) is considered to be one of the main components responsible for the health benefits of the Mediterranean diet, particularly against atherosclerosis where peripheral blood mononuclear cells (PBMNCs) ...
  • Huerta Cepas, Jaime; Capella Gutiérrez, Salvador Jesús; Pryszcz, Leszek P.; Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973- (Oxford University Press, 2014)
    Phylogenetic trees representing the evolutionary relationships of homologous genes are the entry point for many evolutionary analyses. For instance, the use of a phylogenetic tree can aid in the inference of orthology and ...
  • Bellora Pereyra, Nicolás; Farré, Domènec; Albà Soler, Mar (BioMed Central, 2007)
    Background: The arrangement of regulatory motifs in gene promoters, or promoter architecture, is the result of mutation and selection processes that have operated over many millions of years. In mammals, tissue-specific ...
  • Jostins, Luke; Jaeger, Johannes (BioMed Central, 2010)
    Background: The use of reverse engineering methods to infer gene regulatory networks by fitting mathematical models to gene expression data is becoming increasingly popular and successful. However, increasing model complexity ...
  • Romagné, Frédéric; Santesmasses, Didac; White, Louise; Sarangi, Gaurab K.; Mariotti, Marco; Hübler, Ron; Weihmann, Antje; Parra, Genís; Gladyshev, Vadim N.; Guigó Serra, Roderic; Castellano, Sergi (Oxford University Press, 2014)
    SelenoDB (http://www.selenodb.org) aims to provide high-quality annotations of selenoprotein genes, proteins and SECIS elements. Selenoproteins are proteins that contain the amino acid selenocysteine (Sec) and the first ...
  • Traeger, Stefanie; Altegoer, Florian; Freitag, Michael; Gabaldón Estevan, Juan Antonio, 1973-; Kempken, Frank; Kumar, Abhishek; Marcet Houben, Marina; Pöggeler, Stefanie; Stajich, Jason E.; Nowrousian, Minou (Public Library of Science (PLoS), 2013)
    Fungi are a large group of eukaryotes found in nearly all ecosystems. More than 250 fungal genomes have already been sequenced, greatly improving our understanding of fungal evolution, physiology, and development. However, ...
  • Prado Martínez, Javier; Hernando Herráez, Irene; Lorente-Galdós, Belén, 1981-; Dabad, Marc; Ramírez Bellido, Òscar; Baeza Delgado, Carlos; Morcillo Suárez, Carlos; Alkan, Can; Hormozdiari, Fereydoun; Raineri, Emanuele; Estellé, Jordi; Fernández Callejo, Marcos; Vallès, Mònica; Ritscher, Lars; Schöneberg, Torsten; Calle Mustienes, Elisa de la; Casillas, Sònia; Rubio Acero, Raquel; Melé Messeguer, Marta, 1982-; Engelken, Johannes; Cáceres, Mario; Gómez Skarmeta, José Luis; Gut, Marta; Bertranpetit, Jaume, 1952-; Gut, Ivo G.; Abelló, Teresa; Eichler, Evan E.; Mingarro, Ismael; Lalueza Fox, Carles, 1965-; Navarro i Cuartiellas, Arcadi, 1969-; Marquès i Bonet, Tomàs, 1975- (BioMed Central, 2013)
    BACKGROUND: The only known albino gorilla, named Snowflake, was a male wild born individual from Equatorial Guinea who lived at the Barcelona Zoo for almost 40 years. He was diagnosed with non-syndromic oculocutaneous ...
  • Mitrovic, Sandra; Nogueira, Cristina; Cantero Recasens, Gerard, 1984-; Kiefer, Kerstin; Fernández-Fernández, José Manuel, 1967-; Popoff, Jean-François; Casano, Laetitia; Bard, Frederic A.; Gómez, Raul; Valverde, M. A. (Miguel Ángel), 1963-; Malhotra, Vivek (eLife, 2013)
    Mucin 5AC (MUC5AC) is secreted by goblet cells of the respiratory tract and, surprisingly, also expressed de novo in mucus secreting cancer lines. siRNA-mediated knockdown of 7343 human gene products in a human colonic ...
  • Durán, Elisa; Djebali, Sarah; González, Santi; Flores, Oscar; Mercader, Josep Maria; Guigó Serra, Roderic; Torrents, David; Soler López, Montserrat; Orozco, Modesto (Oxford University Press, 2013)
    Although protein recognition of DNA motifs in promoter regions has been traditionally considered as a critical regulatory element in transcription, the location of promoters, and in particular transcription start sites ...

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