Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Subject "Càncer -- Aspectes genètics"

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Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Subject "Càncer -- Aspectes genètics"

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  • Puente, Xosé S.; Velasco, Gloria; Gutiérrez Fernández, Ana; Bertranpetit, Jaume; King, Mary Claire; López Otín, Carlos (BioMed Central, 2006)
    Background: Cancer is a major medical problem in modern societies. However, the incidence of this disease in non-human primates is very low. To study whether genetic differences between human and chimpanzee could contribute ...
  • Castillejo, Adela; Guarinos, Carla; Martínez Canto, Ana; Barbera, Victor Manuel; Egoavil, Cecilia; Castillejo, Maria Isabel; Pérez Carbonell, Lucía; Sánchez Heras, Ana Beatriz; Segura, Ángel; Ochoa, Enrique; Lazaro, Rafael; Ruiz Ponte, Clara; Bujanda, Luis; Andreu, Montserrat; Castells, Antoni; Carracedo, Ángel; Llor, Xavier; Clofent, Juan; Alenda, Cristina; Paya, Artemio; Jover, Rodrigo; Soto, José Luis (BioMed Central, 2011)
    Background: Lynch syndrome (LS) is an autosomal dominant inherited cancer syndrome characterized by early onset cancers of the colorectum, endometrium and other tumours. A significant proportion of DNA variants in LS ...
  • Solé, Xavier; Hernández, Pilar; López de Heredia, Miguel de; Armengol Dulcet, Lluís; Rodríguez Santiago, Benjamín; Gómez, Laia; Maxwell, Christopher A.; Aguilo, Fernando; Condom, Enric; Abril, Jesús; Pérez Jurado, Luis Alberto; Estivill, Xavier, 1955-; Nunes, Virginia; Capellá, Gabriel; Gruber, Stephen B.; Moreno, Víctor; Pujana, Miguel Ángel (BioMed Central, 2008)
    Background: Germline genetic variation is associated with the differential expression of many human genes. The phenotypic effects of this type of variation may be important when considering susceptibility to common genetic ...
  • Conde Pueyo, Núria; Munteanu, Andreea; Solé, Ricard V.; Rodríguez Caso, Carlos (BioMed Central, 2009)
    Background: Two genes are called synthetic lethal (SL) if mutation of either alone is not lethal, but mutation of both leads to death or a significant decrease in organism's fitness. The detection of SL gene pairs constitutes ...
  • Aragüés Peleato, Ramón; Sander, Chris; Oliva, Baldomero (BioMed Central, 2008)
    Background: Systematic approaches for identifying proteins involved in different types of cancer are needed. Experimental techniques such as microarrays are being used to characterize cancer, but validating their results ...
  • Furney, Simon J.; Higgins, Desmond G.; Ouzounis, Christos A.; López Bigas, Núria (BioMed Central, 2006)
    Background: One of the main goals of cancer genetics is to identify the causative elements at the molecular level leading to cancer. Results: We have conducted an analysis of a set of genes known to be involved in cancer ...

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