Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Issue Date

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Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Issue Date

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  • Berrendero Díaz, Fernando; Kieffer, Brigitte L.; Maldonado, Rafael, 1961- (Society for Neuroscience, 2002)
    The involvement of μ-opioid receptors in different behavioral responses elicited by nicotine was explored by using μ-opioid receptor knock-out mice. The acute antinociceptive responses induced by nicotine in the tail-immersion ...
  • Muñoz López, Francisco José, 1964-; Opazo, Carlos; Gil Gómez, Gabriel; Tapia, Gladys; Fernández, Virginia; Valverde, M. A. (Miguel Ángel); Inestrosa, Nibaldo C. (Society for Neuroscience, 2002)
    Amyloid β-peptide (Aβ) fibril deposition on cerebral vessels produces cerebral amyloid angiopathy that appears in the majority of Alzheimer's disease patients. An early onset of a cerebral amyloid angiopathy variant called ...
  • Parra Farré, Genís; Agarwal, Pankaj; Abril Ferrando, Josep Francesc; Wiehe, Thomas; Fickett, James W.; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2003)
    The completion of the sequencing of the mouse genome promises to help predict human genes with greater accuracy. While current ab initio gene prediction programs are remarkably sensitive (i.e., they predict at least a ...
  • García Martínez, Montse; Schiaffino, Anna; Fernández, Esteve; Martí, Mercè; Saltó i Cerezuela, Esteve; Pérez Albarracín, Glòria; Peris, Mercè; Borrell i Thió, Carme; Nieto, F. Javier; Borrás, Josep M. (BioMed Central, 2003)
    Background: The aim of this report is to describe the main characteristics of the design, including response rates, of the Cornella Health Interview Survey Follow-up Study. Methods: The original cohort consisted of 2,500 ...
  • Cheung, Joseph; Estivill Pallejà, Xavier; Khaja, Razi; MacDonald, Jeffrey R; Lau, Ken; Tsui, Lap-Chee; Scherer, Stephen W (BioMed Central, 2003)
    Background: Previous studies have suggested that recent segmental duplications, which are often involved in chromosome rearrangements underlying genomic disease, account for some 5% of the human genome. We have developed ...
  • Guigó Serra, Roderic (Centre de Supercomputació de Catalunya, 2003)
  • Fiz, José Antonio; Jané, Raimon; Torres, Abel; Morera, Josep; Galdiz, Batxi; Gea Guiral, Joaquim; Grassino, Alejandro (BioMed Central, 2004)
    Background: Non-invasive monitoring of respiratory muscle function is an area of increasing research interest, resulting in the appearance of new monitoring devices, one of these being piezoelectric contact sensors. The ...
  • Albà Soler, Mar; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2004)
    Amino acid tandem repeats, also called homopolymeric tracts, are extremely abundant in eukaryotic proteins. To gain insight into the genome-wide evolution of these regions in mammals, we analyzed the repeat content in a ...
  • Ozaita Mintegui, Andrés; Petit-Jacques, Jerome; Völgyi, Béla; Ho, Chi Sun; Joho, Rolf H.; Bloomfield, Stewart A.; Rudy, Bernardo (Society for Neuroscience, 2004)
    Direction-selective retinal ganglion cells show an increased activity evoked by light stimuli moving in the preferred direction. This selectivity is governed by direction-selective inhibition from starburst amacrine cells ...
  • Huang, Hui; Winter, Eitan E; Wang, Huajun; Weinstock, Keith G; Xing, Heming; Goodstadt, Leo; Stenson, Peter D; Cooper, David N; Smith, Douglas; Ponting, Chris P; Albà Soler, Mar; Fechtel, Kim (BioMed Central, 2004)
    Background: Model organisms have contributed substantially to our understanding of the etiology of human disease as well as having assisted with the development of new treatment modalities. The availability of the human, ...
  • Wahl, Matthias B.; Caldwell, Randolph B.; Kierzek, Andrzej M.; Arakawa, Hirosi; Eyras Jiménez, Eduardo; Hubner, Nina; Jung, Christian; Soeldenwagner, Manuel; Cervelli, Manuela; Wang, Yan-Dong; Liebscher, Volkmar; Buerstedde, Jean-Marie (BioMed Central, 2004)
    Background: The understanding of whole genome sequences in higher eukaryotes depends to a large degree on the reliable definition of transcription units including exon/intron structures, translated open reading frames ...
  • Aso Pérez, Ester; Maldonado, Rafael, 1961-; Murtra, Patricia; Balerio, Graciela N.; Berrendero Díaz, Fernando (Wiley-Blackwell, 2004)
    The possible interactions between Delta9-tetrahydrocannabinol (THC) and nicotine remain unclear in spite of the current association of cannabis and tobacco in humans. The aim of the present study was to explore the ...
  • González-Neira, Anna; Calafell i Majo, Francesc; Navarro Cuartiellas, Arcadi; Lao Grueso, Oscar, 1976-; Cann, Howard; Comas Martínez, David; Bertranpetit, Jaume, 1952- (BioMed Central, 2004)
    Recent studies of haplotype diversity in a number of genomic regions have suggested that long stretches of DNA are preserved in the same chromosome, with little evidence of recombination events. The knowledge of the extent ...
  • Abril Ferrando, Josep Francesc; Castelo, Robert; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2005)
    We have carried out an initial analysis of the dynamics of the recent evolution of the splice-sites sequences on a large collection of human, rodent (mouse and rat), and chicken introns. Our results indicate that the ...
  • Castelo, Robert; Reymond, Alexandre; Wyss, Carine; Cámara, Francisco; Parra Farré, Genís; Antonarakis, Stylianos E.; Guigó Serra, Roderic; Eyras Jiménez, Eduardo (Oxford University Press, 2005)
    The recent availability of the chicken genome sequence poses the question of whether there are human protein-coding genes conserved in chicken that are currently not included in the human gene catalog. Here, we show, using ...
  • Taskov, Kalin; Chapple, Charles E.; Kryukov, Gregory V.; Castellano, Sergi; Lobanov, Alexey V.; Korotkov, Konstantin V.; Guigó Serra, Roderic; Gladyshev, Vadim N. (Oxford University Press, 2005)
    Selenocysteine (Sec) is co-translationally inserted into selenoproteins in response to codon UGA with the help of the selenocysteine insertion sequence (SECIS) element. The number of selenoproteins in animals varies, with ...
  • Boada Centeno, Núria; Planas Iglesias, Joan, 1980-; Oliva Miguel, Baldomero (BioMed Central, 2005)
    Comparative modeling is becoming an increasingly helpful technique in microbial cell factories as the knowledge of the three-dimensional structure of a protein would be an invaluable aid to solve problems on protein ...
  • Lalueza Fox, Carles; Castresana, José; Sampietro Bergua, Mª Lourdes; Marquès i Bonet, Tomàs, 1975-; Alcover, Josep Antoni; Bertranpetit, Jaume (BioMed Central, 2005)
    Background: Myotragus balearicus was an endemic bovid from the Balearic Islands (Western Mediterranean) that became extinct around 6,000-4,000 years ago. The Myotragus evolutionary lineage became isolated in the islands ...
  • Berrendero Díaz, Fernando; Mendizábal, Victoria; Robledo, M. Patricia; Galeote González, Lola; Bilkei Gorzo, Andras; Zimmer, Andreas; Maldonado, Rafael, 1961- (Society for Neuroscience, 2005)
    It has been shown previously that the endogenous opioid system may be involved in the behavioral effects of nicotine. In the present study, the participation of endogenous enkephalins on nicotine responses has been ...
  • Eyras Jiménez, Eduardo; Reymond, Alexandre; Castelo, Robert; Bye, Jacqueline M.; Cámara, Francisco; Flicek, Paul; Huckle, Elizabeth J.; Parra Farré, Genís; Shteynberg, David D.; Wyss, Carine; Rogers, Jane; Antonarakis, Stylianos E.; Birney, Ewan; Guigó Serra, Roderic; Brent, Michael R. (BioMed Central, 2005)
    Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This is particularly true for genomes for which ...

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