Foresti, Ombretta; Ruggiano, Annamaria, 1985-; Hannibal-Bach, Hans K.; Ejsing, Christer S.; Carvalho, Pedro C.
(eLife, 2013)
Sterol homeostasis is essential for the function of cellular membranes and requires feedback inhibition of HMGR, a rate-limiting enzyme of the mevalonate pathway. As HMGR acts at the beginning of the pathway, its regulation ...