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Visualitza Departament de Medicina i Ciències de la Vida per autoria

Visualitza Departament de Medicina i Ciències de la Vida per autoria "Agostini, Federico, 1985-"

Ara mostrant els elements 1-7 de 7

catRAPID omics: a web server for large-scale prediction of protein-RNA interactions

Agostini, Federico, 1985-; Zanzoni, Andreas; Klus, Petr, 1985-; Marchese, Domenica, 1986-; Cirillo, Davide; Tartaglia, Gian Gaetano (Oxford University Press, 2013)

SUMMARY: Here we introduce catRAPID omics, a server for large-scale calculations of protein-RNA interactions. Our web server allows (i) predictions at proteomic and transcriptomic level; (ii) use of protein and RNA sequences ...
ccSOL omics: a webserver for solubility prediction of endogenous and heterologous expression in Escherichia coli

Agostini, Federico, 1985-; Cirillo, Davide; Livi, Carmen Maria; Ponti, Riccardo delli; Tartaglia, Gian Gaetano (Oxford University Press, 2014)

SUMMARY: Here we introduce ccSOL omics, a webserver for large-scale calculations of protein solubility. Our method allows (i) proteome-wide predictions; (ii) identification of soluble fragments within each sequences; (iii) ...
DnaK functions as a central hub in the E. colichaperone network

Calloni, Giulia; Chen, Taotao; Schermann, Sonya M.; Chang, Hung-chun; Genevaux, Pierre; Agostini, Federico, 1985-; Tartaglia, Gian Gaetano (Elsevier, 2012)

Cellular chaperone networks prevent potentially toxic protein aggregation and ensure proteome integrity. Here, we used Escherichia coli as a model to understand the organization of these networks, focusing on the cooperation ...
Neurodegenerative diseases: quantitative predictions of protein-RNA interactions

Cirillo, Davide; Agostini, Federico, 1985-; Klus, Petr, 1985-; Marchese, Domenica, 1986-; Rodríguez, Silvia; Bolognesi, Benedetta; Tartaglia, Gian Gaetano (Cold Spring Harbor Laboratory Press (CSHL Press), 2013)

Increasing evidence indicates that RNA plays an active role in a number of neurodegenerative diseases. We recently introduced a theoretical framework, catRAPID, to predict the binding ability of protein and RNA molecules. ...
Principles of self-organization in biological pathways: a hypothesis on the autogenous association of alpha-synuclein

Zanzoni, Andreas; Marchese, Domenica, 1986-; Agostini, Federico, 1985-; Bolognesi, Benedetta; Cirillo, Davide; Botta-Orfila, Maria; Livi, Carmen Maria; Rodriguez-Mulero, Silvia; Tartaglia, Gian Gaetano (Oxford University Press, 2013)

Previous evidence indicates that a number of proteins are able to interact with cognate mRNAs. These autogenous associations represent important regulatory mechanisms that control gene expression at the translational level. ...
SeAMotE: a method for high-throughput motif discovery in nucleic acid sequences

Agostini, Federico, 1985-; Cirillo, Davide; Delli Ponti, Riccardo, 1987-; Tartaglia, Gian Gaetano (BioMed Central, 2014)

BACKGROUND: The large amount of data produced by high-throughput sequencing poses new computational challenges. In the last decade, several tools have been developed for the identification of transcription and splicing ...
X-inactivation: quantitative predictions of protein interactions in the Xist network

Agostini, Federico, 1985-; Cirillo, Davide; Bolognesi, Benedetta; Tartaglia, Gian Gaetano (Oxford University Press, 2013)

The transcriptional silencing of one of the female X-chromosomes is a finely regulated process that requires accumulation in cis of the long non-coding RNA X-inactive-specific transcript (Xist) followed by a series of ...