Browsing Departament de Ciències Experimentals i de la Salut by Title

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Browsing Departament de Ciències Experimentals i de la Salut by Title

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  • Mann, Christopher J.; Perdiguero, Eusebio, 1968-; Kharraz, Yacine; Aguilar, Susana; Pessina, Patrizia; Serrano, Antonio L.; Muñoz Cánoves, Pura, 1962- (BioMed Central, 2011)
    The repair process of damaged tissue involves the coordinated activities of several cell types in response to local and systemic signals. Following acute tissue injury, infiltrating inflammatory cells and resident stem ...
  • Noguera, José L.; Rodríguez, Carmen; Varona, Luis; Tomàs, Anna; Muñoz, Gloria; Ramírez, Óscar; Barragán, Carmen; Arqué, Meritxell; Bidanel, Jean P.; Amills, Marcel; Ovilo, Cristina; Sánchez, Armand (BioMed Central, 2009)
    Background: Prolificacy is the most important trait influencing the reproductive efficiency of pig production systems. The low heritability and sex-limited expression of prolificacy have hindered to some extent the improvement ...
  • Blanco, Enrique; Farré, Domènec; Albà Soler, Mar; Messeguer, Xavier; Guigó Serra, Roderic (Oxford University Press, 2006)
    Information about the genomic coordinates and the sequence of experimentally identified transcription factor binding sites is found scattered under a variety of diverse formats. The availability of standard collections of ...
  • Zimmer, Andreas; Valjent, Emmanuel; König, Monika; Zimmer, Anne M.; Robledo, M. Patricia; Hahn, Heidi; Valverde, Olga; Maldonado, Rafael, 1961- (Society for Neuroscience, 2001)
    The involvement of dynorphin on Delta-9-tetrahydrocannabinol (THC) and morphine responses has been investigated by using mice with a targeted inactivation of the prodynorphin (Pdyn) gene. Dynorphin-deficient mice show ...
  • Marquès i Bonet, Tomàs, 1975-; Kidd, Jeffrey M.; Ventura, Mario; Graves, Tina A.; Cheng, Ze; Hillier, LaDeana W.; Jiang, Zhaoshi; Baker, Carl; Malfavon-Borja, Ray; Fulton, Lucinda A.; Alkan, Can; Aksay, Gozde; Girirajan, Santhosh; Siswara, Priscillia; Chen, Lin; Cardone, Maria Francesca; Navarro i Cuartiellas, Arcadi, 1969-; Mardis, Elaine R.; Wilson, Richard K.; Eichler, Evan E. (Nature Publishing Group, 2009)
    It is generally accepted that the extent of phenotypic change between human and great apes is dissonant with the rate of molecular change. Between these two groups, proteins are virtually identical, cytogenetically there ...
  • Guigó Serra, Roderic; Manichanh, Chaysavanh; Chapple, Charles E.; Frangeul, Lionel; Gloux, Karine; Dore, Joel (Oxford University Press, 2008)
    The construction of metagenomic libraries has permitted the study of microorganisms resistant to isolation and the analysis of 16S rDNA sequences has been used for over two decades to examine bacterial biodiversity. Here, ...
  • Acosta, Juan Carlos; Banito, Ana; Wuestefeld, Torsten; Georgilis, Athena; Janich, Peggy, 1981-; Morton, Jennifer P.; Athineos, Dimitris; Kang, Tae-Won; Lasitschka, Felix; Andrulis, Mindaugas; Pascual, Gloria; Morris, Kelly J.; Khan, Sadaf; Jin, Hong; Dharmalingam, Gopuraja; Snijders, Ambrosius P.; Carroll, Thomas; Capper, David; Pritchard, Catrin; Inman, Gareth J.; Longerich, Thomas; Sansom, Owen J.; Aznar Benitah, Salvador; Zender, Lars; Gil, Jesús (Nature Publishing Group, 2013)
    Oncogene-induced senescence (OIS) is crucial for tumour suppression. Senescent cells implement a complex pro-inflammatory response termed the senescence-associated secretory phenotype (SASP). The SASP reinforces senescence, ...
  • Matthes, Hans W. D.; Smadja, C.; Valverde, Olga; Vonesch, J. L.; Foutz, A. S.; Boudinot, E.; Denavit-Saubié, M.; Severini, Cintia; Negri, Lucia; Roques, B. P.; Maldonado, Rafael, 1961-; Kieffer, Brigitte L. (Society for Neuroscience, 1998)
    Previous pharmacological studies have indicated the possible existence of functional interactions between μ-, δ- and κ-opioid receptors in the CNS. We have investigated this issue using a genetic approach. Here we describe ...
  • Moreno Estrada, Andrés; Aparicio Prat, Estel; Sikora, Martin; Engelken, Johannes; Ramírez Soriano, Anna; Calafell i Majó, Francesc; Bosch Fusté, Elena (BioMed Central, 2010)
    Background: The human FOXI1 gene codes for a transcription factor involved in the physiology of the inner ear, testis, and kidney. Using three interspecies comparisons, it has been suggested that this may be a gene ...
  • Guigó Serra, Roderic; Sammeth, Michael; Foissac, Sylvain (Public Library of Science (PLoS), 2008)
    Understanding the molecular mechanisms responsible for the regulation of the transcriptome present in eukaryotic cells is one of the most challenging tasks in the postgenomic era. In this regard, alternative splicing (AS) ...
  • Sikora, Martin; Laayouni, Hafid; Calafell i Majó, Francesc; Comas, David; Bertranpetit, Jaume (Nature Publishing Group, 2011)
    Studies of large sets of SNP data have proven to be a powerful tool in the analysis of the genetic structure of human populations. In this work, we analyze genotyping data for 2,841 SNPs in 12 Sub-Saharan African populations, ...
  • Muiños Gimeno, Margarita; Guidi, Mònica; Kagerbauer, Birgit; Martín Santos, Rocío; Navinés, Ricard; Alonso, Pino; Menchón, José M.; Gratacós Mayora, Mònica; Estivill, Xavier, 1955-; Espinosa Parrilla, Yolanda (Wiley-Blackwell, 2009)
    Genetic and functional data indicate that variation in the expression of the neurotrophin-3 receptor gene (NTRK3) may have an impact on neuronal plasticity, suggesting a role for NTRK3 in the pathophysiology of anxiety ...
  • Puig, Carme; García Algar, Oscar; Monleón, Toni; Pacifici, Roberta; Zuccaro, Piergiorgio; Sunyer Deu, Jordi; Figueroa, Cecilia; Pichini, Simona; Vall Combelles, Oriol (BioMed Central, 2008)
    Background: Awareness of the negative effects of smoking on children's health prompted a decrease in the self-reporting of parental tobacco use in periodic surveys from most industrialized countries. Our aim is to assess ...
  • Mercader Bigas, Josep Maria; Ribasés, Marta; Gratacós Mayora, Mònica; González, Juan Ramón; Bayés, Mònica; Cid Ibeas, Rafael de; Badía, Anna; Fernández Aranda, Fernando; Estivill, Xavier, 1955- (John Wiley & Sons, 2007)
    Murine models and association studies in eating disorder (ED) patients have shown a role for the brain-derived neurotrophic factor (BDNF) in eating behavior. Some studies have shown association of BDNF -270C/T single-nucleotide ...
  • Vidal Iglesias, Berta; Ardite, Esther; Suelves, Mònica; Ruiz Bonilla, Vanesa, 1979-; Janué, Anna; Flick, Matthew J.; Degen, Jay L.; Serrano, Antonio L.; Muñoz Cánoves, Pura, 1962- (Oxford University Press, 2012)
    In Duchenne muscular dystrophy (DMD), a persistently altered and reorganizing extracellular matrix (ECM) within inflamed muscle promotes damage and dysfunction. However, the molecular determinants of the ECM that mediate ...
  • Bosch Pages, Nina; Escaramís, Geòrgia; Mercader Bigas, Josep Maria; Armengol Dulcet, Lluís; Estivill, Xavier, 1955- (Elsevier, 2008)
    Copy number variants contribute extensively to inter-individual genomic differences, but little is known about their inter-population variability and diversity. In a previous study (Bosch et al., 2007; 16:2572-2582), we ...
  • Morancho Armisen, Beatriz; Minguillón Pedreño, Jordi; Molkentin, Jeffery D.; López Rodríguez, M. Cristina; Aramburu Beltrán, José Francisco (BioMed Central, 2008)
    Background: The transcription factor NFAT5/TonEBP regulates the response of mammalian cells to hypertonicity. However, little is known about the physiopathologic tonicity thresholds that trigger its transcriptional activity ...
  • Guigó Serra, Roderic; Agarwal, Pankaj; Abril Ferrando, Josep Francesc; Burset Albareda, Moisès; Fickett, James W. (Cold Spring Harbor Laboratory Press-CSHL Press, 2000)
    One of the first useful products from the human genome will be a set of predicted genes. Besides its intrinsic scientific interest, the accuracy and completeness of this data set is of considerable importance for human ...
  • Hagen, Ferry; Ceresini, Paulo C.; Polacheck, Itzhack; Ma, Hansong; Nieuwerburgh, Filip van; Gabaldón Estevan, Juan Antonio, 1973-; Kagan, Sarah; Pursall, E. Rhiannon; Hoogveld, Hans L.; Iersel, Leo J. van; Klau, Gunnar W.; Kelk, Steven M.; Stougie, Leen; Bartlett, Karen H.; Voelz, Kerstin; Pryszcz, Leszek P.; Castañeda, Elizabeth; Lazera, Marcia; Meyer, Wieland; Deforce, Dieter; Meis, Jacques F.; May, Robin C.; Klaassen, Corné H. W.; Boekhout, Teun (Public Library of Science (PLoS), 2013)
    Over the past two decades, several fungal outbreaks have occurred, including the high-profile 'Vancouver Island' and 'Pacific Northwest' outbreaks, caused by Cryptococcus gattii, which has affected hundreds of otherwise ...
  • Stamatoyannopoulos, John A.; Guigó Serra, Roderic; Djebali, Sarah; Lagarde, Julien; Adams, Leslie B. (BioMed Central, 2012)
    To complement the human Encyclopedia of DNA Elements (ENCODE) project and to enable a broad range of mouse genomics efforts, the Mouse ENCODE Consortium is applying the same experimental pipelines developed for human ENCODE ...

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