Documents de recerca, en accés obert, com ara articles de revista, llibres, comunicacions, ponències o posters a jornades i congressos, etc., del Departament de Ciències Experimentals i de la Salut de la UPF.
Context: Bladder cancer (BLCA) is a highly prevalent tumour and a health problem worldwide, especially among men. Recent work has highlighted the relevance of the tumour microenvironment (TME) in cancer biology with ...
Buttery, Sara C.; Buekers, Joren; Delgado Ortiz, Laura; García Aymerich, Judith; Gimeno Santos, Elena, 1980-; Koch, Sarah; Hopkinson, Nicholas S.(European Respiratory Society, 2023)
Background: Reduced mobility is a central feature of COPD. Assessment of mobility outcomes that can be measured digitally (digital mobility outcomes (DMOs)) in daily life such as gait speed and steps per day is increasingly ...
Background: Observations from different fields of research coincide in indicating that a defective gamma-aminobutyric acid (GABA) interneuron system may be among the primary factors accounting for the varied clinical ...
Background: Migration is a multi-stage social process linked to traumatic event exposure and a notably increased risk of psychosis. Although these conditions affect refugee and non-refugee immigrants, prior trauma research ...
Kirkeleit, Jorunn; Carsin, Anne-Elie; García Aymerich, Judith; Svanes, Cecilie(Elsevier, 2023)
Background: We aimed to assess whether exposure to risk factors in early life from conception to puberty continue to contribute to lung function decline later in life by using a pooled cohort comprising approx. 11,000 ...
Background: Acute respiratory distress syndrome (ARDS) subphenotypes differ in outcomes and treatment responses. Subphenotypes in high-flow nasal oxygen (HFNO)-treated ARDS patients have not been investigated. Objectives: ...
Cremer, Julian; Medrano Sandonas, Leonardo; Tkatchenko, Alexandre; Clevert, Djork-Arné; De Fabritiis, Gianni(American Chemical Society (ACS), 2023)
Predictive modeling of toxicity is a crucial step in the drug discovery pipeline. It can help filter out molecules with a high probability of failing in the early stages of de novo drug design. Thus, several machine learning ...
Parada-Gereda, Henry M.; Tibaduiza, Adriana L.; Rico-Mendoza, Alejandro; Molano Franco, Daniel; Nieto, Victor H.; Arias-Ortiz, Wanderley A.; Pérez-Terán, Purificación; Masclans Enviz, Joan Ramon(BioMed Central, 2023)
Background: Several measurements have been used to predict the success of weaning from mechanical ventilation; however, their efficacy varies in different studies. In recent years, diaphragmatic ultrasound has been used ...
Conservative surgery is the preferred treatment in the management of breast cancer followed by adjuvant whole-breast irradiation. Since the tumor bed is the main site of relapse, boost doses are conveniently administered ...
Mason, Natasha L.; Szabo, Attila; Kuypers, Kim PC; Mallaroni, Pablo A.; Torre Fornell, Rafael de la; Reckweg, Johannes T.; Tse, Desmond H.Y.; Hutten, Nadia R.P.W.; Feilding, Amanda; Ramaekers, Johannes G.(Elsevier, 2023)
Patients characterized by stress-related disorders such as depression display elevated circulating concentrations of pro-inflammatory cytokines and a hyperactive HPA axis. Psychedelics are demonstrating promising results ...
Introduction: In stable patients with pulmonary arterial hypertension (PAH), pulmonary rehabilitation (PR) is an effective, safe and cost-effective non-pharmacological treatment. However, the effects of PR on vascular ...
Elliott, Jessie A.; Markar, Sheraz R.; Klevebro, Fredrik; Johar, Asif; Goense, Lucas; Lagergren, Pernilla; Zaninotto, Giovanni; van Hillegersberg, Richard; van Berge Henegouwen, Mark I.; Nilsson, Magnus; Hanna, George B.; Reynolds, John Vincent; ENSURE Study Group(Lippincott Williams & Wilkins, 2023)
Objective: To determine the impact of surveillance on recurrence pattern, treatment, survival and health-related quality-of-life (HRQL) following curative-intent resection for esophageal cancer. Summary background data: ...
Brain-age can be inferred from structural neuroimaging and compared to chronological age (brain-age delta) as a marker of biological brain aging. Accelerated aging has been found in neurodegenerative disorders like Alzheimer's ...
The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry ...
Lytras, Theodoros, 1987-; Danis, K.; Dounias, George(National Iranian Oil Company (NIOC) Health Organization, 2016)
Background: Brucellosis is the most common bacterial zoonosis worldwide. Greece has the highest reported incidence among EU countries. However, occupational risk factors have not been well described.Objective: To determine ...