Browsing Recerca: articles, congressos, llibres by Subject "Regulació genètica"

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Browsing Recerca: articles, congressos, llibres by Subject "Regulació genètica"

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  • Cowled, Christopher; Stewart, Cameron R; Likic, Vladimir A; Friedländer, Marc R; Tachedjian, Mary; Jenkins, Kristie A; Tizard, Mark L; Cottee, Pauline; Marsh, Glenn A; Zhou, Peng; Baker, Michelle L; Bean, Andrew G; Wang, Lin-fa (BioMed Central, 2014)
    Background: Bats are a major source of new and emerging viral diseases. Despite the fact that bats carry and shed highly pathogenic viruses including Ebola, Nipah and SARS, they rarely display clinical symptoms of infection. ...
  • Gerstein, Mark B.; Djebali, Sarah; Lagarde, Julien; Pervouchine, Dimitri; Guigó Serra, Roderic; Tanzer, Andrea; Waterston, Robert (Nature Publishing Group, 2014)
    The transcriptome is the readout of the genome. Identifying common features in it across distant species can reveal fundamental principles. To this end, the ENCODE and modENCODE consortia have generated large amounts of ...
  • Abril Ferrando, Josep Francesc; Castelo, Robert; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2005)
    We have carried out an initial analysis of the dynamics of the recent evolution of the splice-sites sequences on a large collection of human, rodent (mouse and rat), and chicken introns. Our results indicate that the ...
  • Tamborero, David; González-Pérez, Abel; Pérez-Llamas, Christian; Déu-Pons, Jordi; Kandoth, Cyriac; Reimand, Jüri; Lawrence, Michael S.; Getz, Gad; Bader, Gary D.; Ding, Li; López Bigas, Núria (Nature Publishing Group, 2013)
    With the ability to fully sequence tumor genomes/exomes, the quest for cancer driver genes can now be undertaken in an unbiased manner. However, obtaining a complete catalog of cancer genes is difficult due to the heterogeneous ...
  • Munteanu, Andrea; Cotterell, James; Solé Vicente, Ricard, 1962-; Sharpe, James (Nature Publishing Group, 2014)
    Interpreting a morphogen gradient into a single stripe of gene-expression is a fundamental unit of patterning in early embryogenesis. From both experimental data and computational studies the feed-forward motifs stand out ...
  • Plass Pórtulas, Mireya; Eyras Jiménez, Eduardo (BioMed Central, 2006)
    Background: Alternatively spliced exons play an important role in the diversification of gene function in most metazoans and are highly regulated by conserved motifs in exons and introns. Two contradicting properties have ...
  • Buxadé, Maria; Lunazzi, Giulia; Minguillón, Jordi; Iborra, Salvador; Berga-Bolaños, Rosa; del Val, Margarita; Aramburu, José (Aramburu Beltrán); López Rodríguez, M. Cristina (Rockefeller University Press, 2012)
    Toll-like receptors (TLRs) engage networks of transcriptional regulators to induce genes essential for antimicrobial immunity. We report that NFAT5, previously characterized as an osmostress responsive factor, regulates ...
  • Chisaguano, Aida M.; Montes, Rosa; Pérez-Berezo, Teresa; Castellote, Ana Isabel; Guerendiain, Marcela; Bustamante Pineda, Mariona; Morales, Eva; García-Esteban, Raquel; Sunyer Deu, Jordi; Franch, Àngels; López-Sabater, M. Carmen (Public Library of Science (PLoS), 2013)
    Background: It is unknown if changes in the gene expression of the desaturase and elongase enzymes are associated with abnormal n-6 long chain polyunsaturated fatty acid (LC-PUFA) levels in children with atopic eczema (AE). ...
  • Casals López, Ferran; Sikora, Martin, 1976-; Laayouni, Hafid, 1968-; Montanucci, Ludovica, 1978-; Muntasell, Aura; Lazarus, Ross; Calafell i Majó, Francesc; Awadalla, Philip; Netea, Mihai G; Bertranpetit, Jaume, 1952- (BioMed Central, 2011)
    Background: Pathogens have represented an important selective force during the adaptation of modern human populations to changing social and other environmental conditions. The evolution of the immune system has therefore ...
  • Maxwell, Christopher A; Guigó Serra, Roderic; Curado, Joao; Tilgner, Hagen, 1980-; Pujana, Miguel Angel (Public Library of Science (PLoS), 2011)
    Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation carriers, accumulation of stem and progenitor cells in normal ...
  • Carey, Lucas; van Dijk, David; Sloot, Peter MA; Kaandorp, Jaap A; Segal, Eran (Public Library of Science (PLoS), 2013)
    The ability of cells to accurately control gene expression levels in response to extracellular cues is limited by the inherently stochastic nature of transcriptional regulation. A change in transcription factor (TF) activity ...
  • Derrien, Thomas; Guigó Serra, Roderic; Johnson, Rory (Frontiers, 2012)
    The transcriptome of a cell is represented by a myriad of different RNA molecules with and without protein-coding capacities. In recent years, advances in sequencing technologies have allowed researchers to more fully ...
  • Meyer, Markus; Vilardell, Josep (Oxford University Press, 2009)
    Removal of introns during pre-mRNA splicing is a critical process in gene expression, and understanding its control at both single-gene and genomic levels is one of the great challenges in Biology. Splicing takes place in ...
  • Gómez, Irene; Peña, Cristina; Herrera, Mercedes; Muñoz, Concepción; Larriba, María Jesús; García, Vanesa; Domínguez, Gemma; Silva, Javier; Rodríguez, Rufo; García de Herreros, Antonio; Bonilla, Felix; García, José M. (Public Library of Science (PLoS), 2011)
    TWIST1 is a transcription factor that belongs to the family of basic helix-loop-helix proteins involved in epithelial-to-mesenchymal transition and invasion processes. The TWIST1 protein possesses oncogenic, drug-resistant, ...

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