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Minimizing recombinations in consensus networks for phylogeographic studies

Parida, Laxmi; Javed, Asif; Melé Messeguer, Marta, 1982-; Calafell i Majó, Francesc; Bertranpetit, Jaume, 1952-; Genographic Consortium (BioMed Central, 2009)

Background: We address the problem of studying recombinational variations in (human) populations. In this paper, our focus is on one computational aspect of the general task: Given two networks G1 and G2, with both mutation ...
A new method to reconstruct recombination events at a genomic scale

Melé Messeguer, Marta, 1982-; Javed, Asif; Pybus Oliveras, Marc, 1985-; Calafell i Majó, Francesc; Parida, Laxmi; Bertranpetit, Jaume, 1952-; Genographic Consortium (Public Library of Science (PLoS), 2010)

Recombination is one of the main forces shaping genome diversity, but the information it generates is often overlooked. A recombination event creates a junction between two parental sequences that may be transmitted to the ...