Visualitza Recerca: articles, congressos, llibres per matèria "Gamma‐secretase"

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Modification of y-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease

Guix Ràfols, Francesc Xavier; Wahle, Tina; Vennekens, Kristel; Snellinx, An; Chávez Gutiérrez, Lucía; Ill-Raga, Gerard, 1982-; Ramos Fernández, Eva, 1984-; Guardia Laguarta, Cristina; Lleó, Alberto; Arimon, Muriel; Berezovska, Oksana; Muñoz López, Francisco José, 1964-; Dotti, Carlos G.; De Strooper, Bart (Wiley-VCH Verlag, 2012)

Inherited familial Alzheimer's disease (AD) is characterized by small increases in the ratio of Aβ42 versus Aβ40 peptide which is thought to drive the amyloid plaque formation in the brain of these patients. Little is known ...