Browsing Recerca: articles, congressos, llibres by Subject "Expressió gènica"

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Browsing Recerca: articles, congressos, llibres by Subject "Expressió gènica"

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  • Fernández Castillo, Noelia; Orejarena Serrano, María-Juliana, 1980-; Ribasés, Marta; Casas, Miguel; Robledo, Patrícia, 1958-; Maldonado, Rafael, 1961-; Cormand, Bru (Wiley-Blackwell, 2012)
    3,4-Methylenedioxymethamphetamine (MDMA, 'ecstasy') is a recreational drug widely used by adolescents and young adults. Although its rewarding effects are well established, there is controversy on its addictive potential. ...
  • Castelo, Robert; Reymond, Alexandre; Wyss, Carine; Cámara, Francisco; Parra Farré, Genís; Antonarakis, Stylianos E.; Guigó Serra, Roderic; Eyras Jiménez, Eduardo (Oxford University Press, 2005)
    The recent availability of the chicken genome sequence poses the question of whether there are human protein-coding genes conserved in chicken that are currently not included in the human gene catalog. Here, we show, using ...
  • Esnaola, Mikel; Puig, Pedro; González ,David; Castelo Valdueza, Robert; González Ruiz, Juan Ramón (BioMed Central, 2013)
    Background: High-throughput RNA sequencing (RNA-seq) offers unprecedented power to capture the real dynamics of gene expression. Experimental designs with extensive biological replication present a unique opportunity to ...
  • Griebel, Thasso; Zacher, Benedikt; Ribeca, Paolo; Raineri, Emanuele; Lacroix, Vincent; Guigó Serra, Roderic; Sammeth, Michael (Oxford University Press, 2012)
    High-throughput sequencing of cDNA libraries constructed from cellular RNA complements (RNA-Seq) naturally provides a digital quantitative measurement for every expressed RNA molecule. Nature, impact and mutual interference ...
  • GTEx Consortium; Lonsdale, John; Guigó Serra, Roderic; Monlong, Jean; Sammeth, Michael; Moore, Helen F. (Nature Publishing Group, 2013)
    Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain unknown. Most associated variants are not ...
  • Nikolaou, Christoforos; Bermúdez, Ignacio; Manichanh, Chaysavanh; García Martínez, José; Guigó Serra, Roderic; Pérez Ortín, José E.; Roca, Joaquim (Oxford University Press, 2013)
    Eukaryotic topoisomerase II (topo II) is the essential decatenase of newly replicated chromosomes and the main relaxase of nucleosomal DNA. Apart from these general tasks, topo II participates in more specialized functions. ...
  • Cheng, Chao; Alexander, Roger; Min, Renqiang; Leng, Jing; Yip, Kevin Y.; Rozowsky, Joel; Yan, Koon-Kiu; Dong, Xianjun; Djebali, Sarah; Ruan, Yijun; Davis, Carrie A.; Carninci, Piero; Lassmann, Timo; Gingeras, Thomas R.; Guigó Serra, Roderic; Birney, Ewan; Weng, Zhiping; Snyder, Michael; Gernstein, Mark (Cold Spring Harbor Laboratory Press (CSHL Press), 2012)
    Statistical models have been used to quantify the relationship between gene expression and transcription factor (TF) binding signals. Here we apply the models to the large-scale data generated by the ENCODE project to study ...

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