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Visualitza Recerca: articles, congressos, llibres per matèria

Visualitza Recerca: articles, congressos, llibres per matèria "Cannabinoid"

Ara mostrant els elements 1-5 de 5

Absence of delta-9-tetrahydrocannabinol dysphoric effects in dynorphin-deficient mice

Zimmer, Andreas; Valjent, Emmanuel; König, Monika; Zimmer, Anne M.; Robledo, Patricia, 1958-; Hahn, Heidi; Valverde Granados, Olga; Maldonado, Rafael, 1961- (Society for Neuroscience, 2001)

The involvement of dynorphin on Delta-9-tetrahydrocannabinol (THC) and morphine responses has been investigated by using mice with a targeted inactivation of the prodynorphin (Pdyn) gene. Dynorphin-deficient mice show ...
Cannabinoid withdrawal syndrome is reduced in pre-proenkephalin knock-out mice

Valverde Granados, Olga; Maldonado, Rafael, 1961-; Valjent, Emmanuel; Zimmer, Anne M.; Zimmer, Andreas (Society for Neuroscience, 2000)

The functional interactions between the endogenous cannabinoid and opioid systems were evaluated in pre-proenkephalin-deficient mice. Antinociception induced in the tail-immersion test by acute Delta9-tetrahydrocannabinol ...
MDMA attenuates THC withdrawal syndrome in mice

Touriño Raposo, Clara; Maldonado, Rafael, 1961-; Valverde Granados, Olga (Springer, 2007)

3, 4-Methylenedioxymethamphetamine (MDMA) and cannabis are widely abused illicit drugs that are frequently consumed in combination. Interactions between these two drugs have been reported in several pharmacological responses ...
The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice

Wilkerson, Jenny L.; Ghosh, Sudeshna; Mustafa, Mohammed; Abdullah, Rehab A.; Niphakis, Micah J.; Cabrera Ortega, Roberto; Maldonado, Rafael, 1961-; Cravatt, Benjamin F.; Lichtman, Aron H. (Elsevier, 2017)

Although opioids are highly efficacious analgesics, their abuse potential and other untoward side effects diminish their therapeutic utility. The addition of non-opioid analgesics offers a promising strategy to reduce ...
When orexins meet cannabinoids: Bidirectional functional interactions

Berrendero Díaz, Fernando, 1971-; Flores de los Heros, África, 1985-; Robledo, Patricia, 1958- (Elsevier, 2018)

A growing body of evidence suggests the existence of biochemical and functional interactions between the endocannabinoid and orexin systems. Cannabinoid and orexin receptors have been shown to form heterodimers in agreement ...