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Visualitza Recerca: articles, congressos, llibres per autoria "Albà Soler, Mar"

Visualitza Recerca: articles, congressos, llibres per autoria "Albà Soler, Mar"

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  • ABS: a database of Annotated regulatory Binding Sites from orthologous promoters
    Blanco, Enrique; Farré, Domènec; Albà Soler, Mar; Messeguer, Xavier; Guigó Serra, Roderic (Oxford University Press, 2006)
    Information about the genomic coordinates and the sequence of experimentally identified transcription factor binding sites is found scattered under a variety of diverse formats. The availability of standard collections of ...
  • Chromatin-bound IκB-alpha regulates a subset of polycomb target genes in differentiation and cancer
    Mulero, María Carmen; Islam, Abul, 1978-; Margalef González, Pol, 1985-; Pecoraro, Matteo, 1984-; Toll Abelló, Agustín; Drechsel, Nils Jan Daniel, 1980-; Charneco, Cristina; Bellora Pereyra, Nicolás; Gallardo Hernández, Fernando; López Arribillaga, Erika, 1986-; Asensio Juan, Elena; Rodilla, Verónica; González, Jessica; Iglesias Coma, Mar; Albà Soler, Mar; Di Croce, Luciano; Villà i Freixa, Jordi; López Bigas, Núria; Keyes, William M., 1973-; Bigas Salvans, Anna; Espinosa Blay, Lluís (Elsevier, 2013)
    IκB proteins are the primary inhibitors of NF-κB. Here, we demonstrate that sumoylated and phosphorylated IκBα accumulates in the nucleus of keratinocytes and interacts with histones H2A and H4 at the regulatory region of ...
  • Comparative analysis of amino acid repeats in rodents and humans
    Albà Soler, Mar; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press-CSHL Press, 2004)
    Amino acid tandem repeats, also called homopolymeric tracts, are extremely abundant in eukaryotic proteins. To gain insight into the genome-wide evolution of these regions in mammals, we analyzed the repeat content in a ...
  • Comparing mitochondrial activity, oxidative stress tolerance, and longevity of thirteen Ascomycota yeast species
    Gröger, Anna; Martínez-Albo, Ilune; Albà Soler, Mar; Ayté del Olmo, José; Vega, Montserrat; Hidalgo Hernando, Elena (MDPI, 2023)
    Aging is characterized by a number of hallmarks including loss of mitochondrial homeostasis and decay in stress tolerance, among others. Unicellular eukaryotes have been widely used to study chronological aging. As a general ...
  • Conserved regions in long non-coding RNAs contain abundant translation and protein–RNA interaction signatures
    Ruiz-Orera, Jorge; Albà Soler, Mar (Oxford University Press, 2020)
    The mammalian transcriptome includes thousands of transcripts that do not correspond to annotated protein-coding genes and that are known as long non-coding RNAs (lncRNAs). A handful of lncRNAs have well-characterized ...
  • De novo assembly and functional annotation of blood transcriptome of loggerhead turtle, and in silico characterization of peroxiredoxins and thioredoxins
    Hernández-Fernández, Javier; Pinzón Velasco, Andrés Mauricio; López Barrera Ellie Anne; Rodríguez Becerra, María Del Pilar; Villanueva Cañas, José Luis, 1984-; Albà Soler, Mar; Mariño Ramírez, Leonardo (Corte Madera, CA : PeerJ Inc., 2021)
    The aim of this study was to generate and analyze the atlas of the loggerhead turtle blood transcriptome by RNA-seq, as well as identify and characterize thioredoxin (Tnxs) and peroxiredoxin (Prdxs) antioxidant enzymes of ...
  • Differences in the evolutionary history of disease genes affected by dominant or recessive mutations
    Furney, Simon J.; Albà Soler, Mar; López Bigas, Núria (BioMed Central, 2006)
    Background: Global analyses of human disease genes by computational methods have yielded important advances in the understanding of human diseases. Generally these studies have treated the group of disease genes uniformly, ...
  • Dissecting the role of low-complexity regions in the evolution of vertebrate proteins
    Radó i Trilla, Núria, 1985-; Albà Soler, Mar (BioMed Central, 2012)
    Low-complexity regions (LCRs) in proteins are tracts that are highly enriched in one or a few aminoacids. Given their high abundance, and their capacity to expand in relatively short periods of time through replication ...
  • Emergence of novel domains in proteins
    Toll i Riera, Macarena, 1984-; Albà Soler, Mar (BioMed Central, 2013)
    Proteins are composed of a combination of discrete, well-defined, sequence domains, associated with specific functions that have arisen at different times during evolutionary history. The emergence of novel domains is ...
  • Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes
    Huang, Hui; Winter, Eitan E; Wang, Huajun; Weinstock, Keith G; Xing, Heming; Goodstadt, Leo; Stenson, Peter D; Cooper, David N; Smith, Douglas; Albà Soler, Mar; Ponting, Chris P; Fechtel, Kim (BioMed Central, 2004)
    Background: Model organisms have contributed substantially to our understanding of the etiology of human disease as well as having assisted with the development of new treatment modalities. The availability of the human, ...
  • Evolutionary trajectories of new duplicated and putative de novo genes
    Montañés, José Carlos; Huertas, Marta; Messeguer, Xavier; Albà Soler, Mar (Oxford University Press, 2023)
    The formation of new genes during evolution is an important motor of functional innovation, but the rate at which new genes originate and the likelihood that they persist over longer evolutionary periods are still poorly ...
  • Extensive post-transcriptional buffering of gene expression in the response to severe oxidative stress in baker's yeast
    Blevins, William Robert, 1987-; Tavella, Teresa; Moro, Simone G.; Blasco Moreno, Bernat, 1986-; Closa-Mosquera, Adrià; Díez Antón, Juana, 1962-; Carey, Lucas, 1980-; Albà Soler, Mar (Nature Research, 2019)
    Cells responds to diverse stimuli by changing the levels of specific effector proteins. These changes are usually examined using high throughput RNA sequencing data (RNA-Seq); transcriptional regulation is generally assumed ...
  • Gene expression profiling in the hibernating primate, cheirogaleus medius.
    Faherty, Sheena L.; Villanueva Cañas, José Luis, 1984-; Klopfer, Peter H.; Albà Soler, Mar; Yoder, Anne D. (Oxford University Press, 2016)
    Hibernation is a complex physiological response that some mammalian species employ to evade energetic demands. Previous work in mammalian hibernators suggests that hibernation is activated not by a set of genes unique to ...
  • Genome-wide analysis of wild-type epstein-barr virus genomes derived from healthy individuals of the 1000 genomes project
    Santpere Baró, Gabriel, 1981-; Darre, Fleur; Blanco, Soledad; Alcami, Antonio; Villoslada, Pablo; Albà Soler, Mar; Navarro i Cuartiellas, Arcadi, 1969- (Oxford University Press, 2014)
    Most people in the world (∼90%) are infected by the Epstein–Barr virus (EBV), which establishes itself permanently in B cells. Infection by EBV is related to a number of diseases including infectious mononucleosis, multiple ...
  • Gut Microbiota Dynamics during Dietary Shift in Eastern African Cichlid Fishes.
    Baldo, Laura; Riera, Joan Lluís; Tooming-Klunderud, Ave; Albà Soler, Mar; Salzburger, Walter (Public Library of Science, 2015)
    The gut microbiota structure reflects both a host phylogenetic history and a signature of adaptation to the host ecological, mainly trophic niches. African cichlid fishes, with their array of closely related species that ...
  • Heterologous microProtein expression identifies LITTLE NINJA, a dominant regulator of jasmonic acid signaling
    Hong, Shin-Young; Sun, Bin; Straub, Daniel; Blaakmeer, Anko; Mineri, Lorenzo; Koch, Jonas; Brinch-Pedersen, Henrik; Holme, Inger B.; Burow, Meike; Lyngs Jørgensen, Hans Jørgen; Albà Soler, Mar; Wenkel, Stephan (National Academy of Sciences, 2020)
    MicroProteins are small, often single-domain proteins that are sequence-related to larger, often multidomain proteins. Here, we used a combination of comparative genomics and heterologous synthetic misexpression to isolate ...
  • High evolutionary turnover of satellite families in Caenorhabditis
    Subirana, Juan A.; Albà Soler, Mar; Messeguer, Xavier (BioMed Central, 2015)
    Background. The high density of tandem repeat sequences (satellites) in nematode genomes and the availability of genome sequences from several species in the group offer a unique opportunity to better understand the ...
  • Impact of uORFs in mediating regulation of translation in stress conditions
    Moro, Simone G.; Hermans, Cedric; Ruiz Orera, Jorge, 1988-; Albà Soler, Mar (BioMed Central, 2021)
    Background: A large fraction of genes contains upstream ORFs (uORFs) in the 5' untranslated region (5'UTR). The translation of uORFs can inhibit the translation of the main coding sequence, for example by causing premature ...
  • Improving genome-wide scans of positive selection by using protein isoforms of similar length
    Villanueva Cañas, José Luis, 1984-; Laurie, Steven, 1973-; Albà Soler, Mar (Oxford University Press, 2013)
    Large-scale evolutionary studies often require the automated construction of alignments of a large number of homologous gene families. The majority of eukaryotic genes can produce different transcripts due to alternative ...
  • Key Role of Amino Acid Repeat Expansions in the Functional Diversification of Duplicated Transcription Factors.
    Radó i Trilla, Núria, 1985-; Arató, Krisztina, 1981-; Pegueroles Queralt, Maria Cinta; Raya, Alicia; Luna, Susana de la; Albà Soler, Mar (Open University Press, 2015)
    The high regulatory complexity of vertebrates has been related to two rounds of whole genome duplication (2R-WGD) that occurred before the divergence of the major vertebrate groups. Following these events, many developmental ...

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