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Browsing Recerca: articles, congressos, llibres by Title

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  • Fernández-Fernández, José Manuel, 1967-; Tomás Mestres, Marta; Vázquez Gómez, Esther; Orio, Patricio; Latorre, Ramón; Sentí Clapés, Mariano; Marrugat de la Iglesia, Jaume; Valverde, M. A. (Miguel Ángel), 1963- (American Society for Clinical Investigation, 2004)
    Hypertension is the most prevalent risk factor for cardiovascular diseases, present in almost 30% of adults. A key element in the control of vascular tone is the large-conductance, Ca(2+)-dependent K(+) (BK) channel. The ...
  • Zhong, Yi; Wang, Zheng; Fu, Baojin; Pan, Fan; Yachida, Shinichi; Dhara, Mousumi; Albesiano, Emilia; Li, Li; Naito, Yoshiki; Vilardell, Felip; Cummings, Christopher; Martinelli, Paola; Li, Ang; Yonescu, Raluca; Ma, Qingyong; Griffin, Constance A; Real, Francisco X.; Iacobuzio Donahue, Christine A (Public Library of Science (PLoS), 2011)
    Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease characterized by late diagnosis and treatment resistance. Recurrent genetic alterations in defined genes in association with perturbations of developmental ...
  • Lopes, Pedro; Nunes, Tiago; Campos, David; Furlong, Laura I., 1971-; Bauer-Mehren, Anna; Sanz, Ferran; Carrascosa, María del Carmen; Mestres i López, Jordi; Kors, Jan A.; Singh, Barat; van Mulligen, Erik M.; van der Lei, Johan; Diallo, Gayo; Avillach, Paul; Ahlberg Helgee, Ernst; Boyer, Scott; Díaz, Carlos; Oliveira, José Luis (Public Library of Science (PLoS), 2013)
    Pharmacovigilance plays a key role in the healthcare domain through the assessment, monitoring and discovery of interactions amongst drugs and their effects in the human organism. However, technological advances in this ...
  • Sansó Martínez, Miriam, 1979-; Vargas Pérez, Itzel; Quintales, Luis; Antequera, Francisco; Ayté del Olmo, José; Hidalgo Hernando, Elena (Oxford University Press, 2011)
    In the fission yeast, the MAP kinase Sty1 and the transcription factor Atf1 regulate up to 400 genes in response to environmental signals, and both proteins have been shown to bind to their promoters in a stress-dependent ...
  • Degenkolbe, Elisa; König, Jana; Zimmer, Julia; Walther, Maria; Reißner, Carsten; Nickel, Joachim; Plöger, Frank; Raspopovic, Jelena, 1984-; Sharpe, James; Dathe, Katarina; Hecht, Jacqueline T.; Mundlos, Stefan; Doelken, Sandra C.; Seemann, Petra (Public Library of Science (PLoS), 2013)
    Growth and Differentiation Factor 5 (GDF5) is a secreted growth factor that belongs to the Bone Morphogenetic Protein (BMP) family and plays a pivotal role during limb development. GDF5 is a susceptibility gene for ...
  • Boronat, Susanna; García Santamarina, Sarela, 1978-; Hidalgo Hernando, Elena (Taylor & Francis (Routledge), 2015)
    Oxidative modifications in proteins have been traditionally considered as hallmarks of damage by oxidative stress and aging. However, oxidants can generate a huge variety of reversible and irreversible modifications in ...
  • Harrow, Jennifer; Denoeud, France; Frankish, Adam; Reymond, Alexandre; Chen, Chao-Kung; Chrast, Jacqueline; Lagarde, Julien; Gilbert, James; Storey, Roy; Swarbreck, David; Rossier, Colette; Ucla, Catherine; Hubbard, Tim J.; Antonarakis, Stylianos E.; Guigó Serra, Roderic (BioMed Central, 2006)
    Background: The GENCODE consortium was formed to identify and map all protein-coding genes within the ENCODE regions. This was achieved by a combination of initial manual annotation by the HAVANA team, experimental ...
  • Harrow, Jennifer; Tanzer, Andrea; Guigó Serra, Roderic; Hubbard, Tim J. (Cold Spring Harbor Laboratory Press (CSHL Press), 2012)
    The GENCODE Consortium aims to identify all gene features in the human genome using a combination of computational analysis, manual annotation, and experimental validation. Since the first public release of this annotation ...
  • Campos-Serna, Javier, 1974-; Ronda Pérez, Elena; Artazcoz Lazcano, Lucía, 1963-; Moen, Bente E; Benavides, Fernando G. (Fernando García) (BioMed Central, 2013)
    Gender inequalities exist in work life, but little is known about their presence in relation to factors examined in occupation health settings. The aim of this study was to identify and summarize the working and employment ...
  • Mayer, Miguel Ángel, 1960-; Bundschus, Markus; Rautschka, Michael; Sanz, Ferran; Furlong, Laura I., 1971- (Public Library of Science (PLoS), 2011)
    Abstract BACKGROUND: Scientists have been trying to understand the molecular mechanisms of diseases to design preventive and therapeutic strategies for a long time. For some diseases, it has become evident that it is not ...
  • Buxadé, Maria; Lunazzi, Giulia; Minguillón Pedreño, Jordi; Iborra, Salvador; Berga-Bolaños, Rosa; del Val, Margarita; Aramburu, José (Aramburu Beltrán); López Rodríguez, M. Cristina (Rockefeller University Press, 2012)
    Toll-like receptors (TLRs) engage networks of transcriptional regulators to induce genes essential for antimicrobial immunity. We report that NFAT5, previously characterized as an osmostress responsive factor, regulates ...
  • Chisaguano, Aida M.; Montes, Rosa; Pérez Berezo, Teresa; Castellote, Ana Isabel; Guerendiain, Marcela; Bustamante Pineda, Mariona; Morales, Eva; García Esteban, Raquel; Sunyer Deu, Jordi; Franch, Àngels; López Sabater, M. Carmen (Public Library of Science (PLoS), 2013)
    Background: It is unknown if changes in the gene expression of the desaturase and elongase enzymes are associated with abnormal n-6 long chain polyunsaturated fatty acid (LC-PUFA) levels in children with atopic eczema (AE). ...
  • Eyras Jiménez, Eduardo; Reymond, Alexandre; Castelo Valdueza, Robert; Bye, Jacqueline M.; Cámara, Francisco; Flicek, Paul; Huckle, Elizabeth J.; Parra Farré, Genís; Shteynberg, David D.; Wyss, Carine; Rogers, Jane; Antonarakis, Stylianos E.; Birney, Ewan; Guigó Serra, Roderic; Brent, Michael R. (BioMed Central, 2005)
    Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This is particularly true for genomes for which ...
  • Boutros, Joseph Jean; Zémor, Gilles; Guillén i Fàbregas, Albert; Biglieri, Ezio (Institute of Electrical and Electronics Engineers (IEEE), 2008)
    A new graph-based construction of generalized low density codes (GLD-Tanner) with binary BCH constituents is described. The proposed family of GLD codes is optimal on block erasure channels and quasi-optimal on block fading ...
  • Rodríguez Pizà, Ignasi; Giorgetti, Alessandra; Izpisúa Belmonte, J. C.; Veiga, Anna; Azqueta, Carmen; Montserrat, Nuria (Nature Publishing Group, 2010)
    Induced pluripotent stem cells (iPSC ) provide an invaluable resource for regenerative medicine as they allow the generation of patient-specific progenitors with potential value for cell therapy. However, in many instances, ...
  • Rodríguez Pizà, Ignasi; Barragan, Montserrat; González, Federico; Izpisúa Belmonte, J. C.; Batlle Morera, Laura; Vassena, Rita; Montserrat, Nuria; Tiscornia, Gustavo (National Academy of Sciences, 2009)
    Induced pluripotent stem (iPS) cells have generated keen interest due to their potential use in regenerative medicine. They have been obtained from various cell types of both mice and humans by exogenous delivery of ...
  • Rojas Castro, Antonio (Hemeroteca Científica Catalana, 2011)
    El presente trabajo tiene como objetivo poner en relación el género literario y el género sexual mediante el estudio del funcionamiento del cronotopo en dos piezas narrativas de Copi (1939-1987). Siguiendo un método ...
  • Casals López, Ferran; Sikora, Martin, 1976-; Laayouni, Hafid, 1968-; Montanucci, Ludovica, 1978-; Muntasell, Aura; Lazarus, Ross; Calafell i Majó, Francesc; Awadalla, Philip; Netea, Mihai G; Bertranpetit, Jaume, 1952- (BioMed Central, 2011)
    Background: Pathogens have represented an important selective force during the adaptation of modern human populations to changing social and other environmental conditions. The evolution of the immune system has therefore ...
  • Robledo, Patrícia, 1958-; Martín García, Elena, 1975-; Aso Pérez, Ester; Maldonado, Rafael, 1961- (Bentham Science Publishers, 2014)
    The pathophysiological mechanisms underlying depression are still poorly understood. An initial hypothesis postulated to explain the substrates of depression was based on the involvement of monoaminergic systems. This early ...
  • Montes Pérez, Antonio; Roca, Gisela; Sabaté, Sergi; Lao, Jose Ignacio; Navarro i Cuartiellas, Arcadi, 1969-; Cantillo, Jordi; Canet, Jaume; GENDOLCAT Study Group (Lippincott, Williams & Wilkins, 2015)
    BACKGROUND: Chronic postsurgical pain (CPSP) has been linked to many surgical settings. The authors aimed to analyze functional genetic polymorphisms and clinical factors that might identify CPSP risk after inguinal hernia ...

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